The human history of the Sabana de Bogotá (SB) in Northern South America has been interpreted both as a continuous process of biocultural evolution and as a process of population discontinuities. Both hypotheses were evaluated on the basis of craniofacial morphology and radiocarbon evidence within a paleoenvironmental framework. The results suggest that the craniofacial morphology changed significantly over time. The investigation of the available radiocarbon database shows that there are hiatuses throughout the Holocene with a major gap between 4700 and 4100 14C BP, which is coincident with strong paleoenvironmental shifts. According to these results, a Population Discontinuity Model is presented which states that during the mid-Holocene (ca. 6000-3800 14C BP) population events as contraction/extinction and/or expansion/dispersals processes influenced by paleoenvironmental changes, promoted the almost complete depopulation of the SB, subsequently allowing the arrival of new hunter-gatherer populations from the Middle Magdalena Valley. Between ca. 2000-1500 14C BP, population expansions of agricultural societies from the east-northeast and/or from the Middle Magdalena Valley penetrated the SB and replaced the Herrera populations. The discontinuity scenario presented is compatible with the concepts of human biogeography and evolutionary geography. ; Fil: Delgado Burbano, Miguel Eduardo. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Departamento de Antropología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina