Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report)
Abstract Background Major depressive disorder (MDD) is a common mood disorder, with a heritability of around 34%. Molecular genetic studies made significant progress and identified genetic markers associated with the risk of MDD; however, progress is slowed down by substantial heterogeneity as MDD is assessed differently across international cohorts. Here, we used a standardized online approach to measure MDD in multiple cohorts in the Netherlands and evaluated whether this approach can be used in epidemiological and genetic association studies of depression. Methods Within the Biobank Netherl... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2020 |
Reihe/Periodikum: | Psychological Medicine ; volume 51, issue 8, page 1345-1354 ; ISSN 0033-2917 1469-8978 |
Verlag/Hrsg.: |
Cambridge University Press (CUP)
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Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27627210 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1017/s0033291720000100 |