BackgroundMajor depressive disorder (MDD) is a common mood disorder, with a heritability of around 34%. Molecular genetic studies made significant progress and identified genetic markers associated with the risk of MDD; however, progress is slowed down by substantial heterogeneity as MDD is assessed differently across international cohorts. Here, we used a standardized online approach to measure MDD in multiple cohorts in the Netherlands and evaluated whether this approach can be used in epidemiological and genetic association studies of depression.MethodsWithin the Biobank Netherlands Interne... Mehr ...
| Verfasser: |
Fedko, Iryna O.
Hottenga, Jouke Jan
Helmer, Quinta
Mbarek, Hamdi
Huider, Floris
Amin, Najaf
Beulens, Joline W.
Bremmer, Marijke A.
Elders, Petra J.
Galesloot, Tessel E.
Kiemeney, Lambertus A.
Van Loo, Hanna M.
Picavet, H. Susan J.
Rutters, Femke
Van Der Spek, Ashley
Van De Wiel, Anne M.
Van Duijn, Cornelia
De Geus, Eco J.C.
Feskens, Edith J.M.
Hartman, Catharina A.
Oldehinkel, Albertine J.
Smit, Jan H.
Verschuren, W. M.Monique
Penninx, Brenda W.J.H.
Boomsma, Dorret I.
Bot, Mariska |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2021 |
| Reihe/Periodikum: |
Fedko , I O , Hottenga , J J , Helmer , Q , Mbarek , H , Huider , F , Amin , N , Beulens , J W , Bremmer , M A , Elders , P J , Galesloot , T E , Kiemeney , L A , Van Loo , H M , Picavet , H S J , Rutters , F , Van Der Spek , A , Van De Wiel , A M , Van Duijn , C , De Geus , E J C , Feskens , E J M , Hartman , C A , Oldehinkel , A J , Smit , J H , Verschuren , W M M , Penninx , B W J H , Boomsma , D I & Bot , M 2021 , ' Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report) ' , Psychological Medicine , vol. 51 , no. 8 , pp. 1345-1354 . https://doi.org/10.1017/S0033291720000100 |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-27624120 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
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https://research.vumc.nl/en/publications/62b985ca-2bc1-4de4-bd41-e471a49434e9 |
