Primary therapy and survival among patients with nodular lymphocyte-predominant Hodgkin lymphoma:a population-based analysis in the Netherlands, 1993–2016

In this nationwide, population-based study, we assessed trends in primary treatment and survival among 687 patients with nodular lymphocyte-predominant Hodgkin lymphoma (75% males; median age, 40 years; and 74% stage-I/II disease) diagnosed in the Netherlands between 1993–2016. There were no noteworthy changes in the application of primary therapy over time among adult patients across the different disease stages and age groups. Survival among various subgroups of adult patients was largely comparable to the expected survival of the general population. A particularly encouraging finding was th... Mehr ...

Verfasser: Posthuma, Hidde L.A.
Zijlstra, Josée M.
Visser, Otto
Lugtenburg, Pieternella J.
Kersten, Marie José
Dinmohamed, Avinash G.
Dokumenttyp: Artikel
Erscheinungsdatum: 2020
Reihe/Periodikum: Posthuma , H L A , Zijlstra , J M , Visser , O , Lugtenburg , P J , Kersten , M J & Dinmohamed , A G 2020 , ' Primary therapy and survival among patients with nodular lymphocyte-predominant Hodgkin lymphoma : a population-based analysis in the Netherlands, 1993–2016 ' , British Journal of Haematology , vol. 189 , no. 1 , pp. 117-121 . https://doi.org/10.1111/bjh.16290
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27623834
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vumc.nl/en/publications/d84c813d-d5e6-441d-80ed-7f8e40e8ff1c

In this nationwide, population-based study, we assessed trends in primary treatment and survival among 687 patients with nodular lymphocyte-predominant Hodgkin lymphoma (75% males; median age, 40 years; and 74% stage-I/II disease) diagnosed in the Netherlands between 1993–2016. There were no noteworthy changes in the application of primary therapy over time among adult patients across the different disease stages and age groups. Survival among various subgroups of adult patients was largely comparable to the expected survival of the general population. A particularly encouraging finding was that young adult patients experienced virtually no excess mortality, as compared to the general population.