Does non-invasive prenatal testing affect the livebirth prevalence of Down syndrome in the Netherlands? A population-based register study
Objective: To evaluate if non-invasive prenatal testing (NIPT) affects livebirth (LB) prevalence of Down syndrome (DS) in the Netherlands. Method: Data from clinical genetics laboratories and the Working Party on Prenatal Diagnosis and Therapy (2014–2018) and previous published data (1991–2013) were used to assess trends for DS LB prevalence and reduction percentage (the net decrease in DS LBs resulting from selective termination of pregnancies). Statistics Netherlands provided general population data. Results: DS LB prevalence increased from 11.6/10,000 in 1991 to 15.9/10,000 in 2002 (regress... Mehr ...
Verfasser: |
de Groot-van der Mooren, Maurike
de Graaf, Gert
Weijerman, Michel E.
Hoffer, Mariette J. V.
Knijnenburg, Jeroen
van der Kevie-Kersemaekers, Anne-Marie M. F.
Kooper, Angelique J. A.
Voorhoeve, Els
Sikkema-Raddatz, Birgit
van Zutven, Laura J. C. M.
Srebniak, Malgorzata Ilona
Huijsdens-van Amsterdam, Karin
Engelen, John J. M.
Smeets, Dominique
van Kaam, Anton H.
Cornel, Martina C. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2021 |
Reihe/Periodikum: |
de Groot-van der Mooren , M , de Graaf , G , Weijerman , M E , Hoffer , M J V , Knijnenburg , J , van der Kevie-Kersemaekers , A-M M F , Kooper , A J A , Voorhoeve , E , Sikkema-Raddatz , B , van Zutven , L J C M , Srebniak , M I , Huijsdens-van Amsterdam , K , Engelen , J J M , Smeets , D , van Kaam , A H & Cornel , M C 2021 , ' Does non-invasive prenatal testing affect the livebirth prevalence of Down syndrome in the Netherlands? A population-based register study ' , Prenatal Diagnosis , vol. 41 , no. 10 , pp. 1351-1359 . https://doi.org/10.1002/pd.6003 , https://doi.org/10.1002/pd.6003 |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27623225 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vumc.nl/en/publications/2d7a2380-52ed-470c-a6df-3a196ca2140c |