Northwestern Europeans are among the tallest of human populations. The increase in body height in these people appears to have reached a plateau, suggesting the ubiquitous presence of an optimal environment in which genetic factors may have exerted a particularly strong influence on human growth. Therefore, we performed a genome-wide association study (GWAS) of body height using 2.2 million markers in 10 074 individuals from three Dutch and one German population-based cohorts. Upon genotyping, the 12 most significantly height-associated single nucleotide polymorphisms (SNPs) from this GWAS in... Mehr ...
Verfasser: |
Estrada, K.
Krawczak, M.
Schreiber, S
van Duijn, K.
Stolk, L.
van Meurs, J.B.J.
Liu, F.
Penninx, B.W.J.H.
Smit, J.H.
Vogelzangs, N.
Hottenga, J.J.
Willemsen, G.
de Geus, E.J.C.
Lorentzon, M.
von Eller-Eberstein, H.
Lips, P.T.A.M.
van Schoor, N.M.
Pop, V.
de Keijzer, J.
Hofman, A.
Aulchenko, Y.S.
Oostra, B.A.
Ohlsson, C.
Boomsma, D.I.
Uitterlinden, A.G.
van Duijn, C.M.
Rivadeneira, F.F.
Kayser, M. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2009 |
Reihe/Periodikum: |
Estrada , K , Krawczak , M , Schreiber , S , van Duijn , K , Stolk , L , van Meurs , J B J , Liu , F , Penninx , B W J H , Smit , J H , Vogelzangs , N , Hottenga , J J , Willemsen , G , de Geus , E J C , Lorentzon , M , von Eller-Eberstein , H , Lips , P T A M , van Schoor , N M , Pop , V , de Keijzer , J , Hofman , A , Aulchenko , Y S , Oostra , B A , Ohlsson , C , Boomsma , D I , Uitterlinden , A G , van Duijn , C M , Rivadeneira , F F & Kayser , M 2009 , ' A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation ' , Human Molecular Genetics , vol. 18 , no. 18 , pp. 3516-3524 . https://doi.org/10.1093/hmg/ddp296 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27622723 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/b8abe358-356a-4208-ac31-3e79da00477d |