Heritability of Polycystic Ovary Syndrome in a Dutch Twin-family study
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. There is evidence for a genetic component in PCOS based on familial clustering of cases. Objective: In the present study, the heritability of PCOS was estimated. Design/Participants: Data from 1332 monozygotic twins (genetically identical) and 1873 dizygotic twins/singleton sisters of twins (who share on average 50% of their segregating genes) registered with The Netherlands Twin Register were used. PCOS was defined as less than nine menstrual cycles and acne or hirsutism... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2006 |
Reihe/Periodikum: | Vink , J M , Sadrzadeh , S , Lambalk , C B & Boomsma , D I 2006 , ' Heritability of Polycystic Ovary Syndrome in a Dutch Twin-family study ' , Journal of Clinical Endocrinology and Metabolism , vol. 91 , no. 6 , pp. 2100-2104 . https://doi.org/10.1210/jc.2005-1494 |
Schlagwörter: | /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27622551 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.vu.nl/en/publications/9439040e-7a7d-4375-840d-e010d5ce0d2a |