Beyond the Global Brain Differences:Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
Background: Carriers of the 1q21.1 distal and 15q11.2 BP1-BP2 copy number variants exhibit regional and global brain differences compared with noncarriers. However, interpreting regional differences is challenging if a global difference drives the regional brain differences. Intraindividual variability measures can be used to test for regional differences beyond global differences in brain structure. Methods: Magnetic resonance imaging data were used to obtain regional brain values for 1q21.1 distal deletion (n = 30) and duplication (n = 27) and 15q11.2 BP1-BP2 deletion (n = 170) and duplicati... Mehr ...
Verfasser: |
Boen, Rune
Kaufmann, Tobias
van der Meer, Dennis
Boomsma, Dorret I.
de Geus, Eco J.C.
van ’t Ent, Dennis
Alnæs, Dag
Andreassen, Ole A.
Sønderby, Ida E. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2024 |
Reihe/Periodikum: |
Boen , R , Kaufmann , T , van der Meer , D , Boomsma , D I , de Geus , E J C , van ’t Ent , D , Alnæs , D , Andreassen , O A , Sønderby , I E & ENIGMA-CNV working group 2024 , ' Beyond the Global Brain Differences : Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers ' , Biological psychiatry , vol. 95 , no. 2 , pp. 147-160 . https://doi.org/10.1016/j.biopsych.2023.08.018 |
Schlagwörter: |
15q11.2 BP1-BP2
/ 1q21.1 distal
/ Brain structure
/ Copy number variants
/ Intraindividual variability
/ Magnetic resonance imaging
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27620634 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/8a2b7005-4fe5-45f2-8746-2c4bcc63acbe |