Associations of brain pathology, cognitive and physical markers with age in cognitively normal individuals aged 60-102 years
The prevalence of brain pathologies increases with age and cognitive and physical function worsen over the lifetime. It is unclear whether these processes show a similar increase with age. We studied the association of markers for brain pathology, cognitive and physical function with age in 288 cognitively normal individuals aged 60-102 years selected from the cross-sectional EMIF-AD PreclinAD and 90+ Study at the Amsterdam UMC. An abnormal score was consistent with a score below the 5th percentile in the 60-70 years old individuals. Prevalence of abnormal scores were estimated using generaliz... Mehr ...
Verfasser: |
Legdeur, Nienke
Tijms, Betty M
Konijnenberg, Elles
den Braber, Anouk
Ten Kate, Mara
Sudre, Carole H
Tomassen, Jori
Badissi, Maryam
Yaqub, Maqsood
Barkhof, Frederik
van Berckel, Bart N
Boomsma, Dorret I
Scheltens, Philip
Holstege, Henne
Maier, Andrea B
Visser, Pieter Jelle |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2020 |
Reihe/Periodikum: |
Legdeur , N , Tijms , B M , Konijnenberg , E , den Braber , A , Ten Kate , M , Sudre , C H , Tomassen , J , Badissi , M , Yaqub , M , Barkhof , F , van Berckel , B N , Boomsma , D I , Scheltens , P , Holstege , H , Maier , A B & Visser , P J 2020 , ' Associations of brain pathology, cognitive and physical markers with age in cognitively normal individuals aged 60-102 years ' , The journals of gerontology. Series A : Biological sciences and medical sciences , vol. 75 , no. 9 , pp. 1609-1617 . https://doi.org/10.1093/gerona/glz180 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27619841 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/397c6871-331d-41b4-9025-cbc63d81a889 |