The increasing importance of histologic grading in tailoring adjuvant systemic therapy in 30,843 breast cancer patients
Purpose: The large variation in histologic grading of invasive breast cancer (IBC) that has been reported likely influences tailoring adjuvant therapy. The role of grading in therapeutic decision-making in daily practice, was evaluated using the Dutch national guidelines for IBC-management. Methods: Synoptic reports of IBC resection-specimens, obtained between 2013 and 2016, were extracted from the nationwide Dutch Pathology Registry, and linked to treatment-data from the Netherlands Cancer Registry. The relevance of grading for adjuvant chemotherapy (aCT) was quantified by identifying patient... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2021 |
Schlagwörter: | Adjuvant systemic treatment / Guideline adherence / Histologic grade / Invasive breast cancer / Real-world data / Neoplasm Grading / Humans / Female / Pathologists / Chemotherapy / Adjuvant / Netherlands/epidemiology / Breast Neoplasms/drug therapy / Oncology / Cancer Research / Journal Article |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27612685 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/443198 |