Oncology patients were found to understand and accept the Trials within Cohorts design
Background and Objective: The Trials within Cohorts design aims to reduce recruitment difficulties and disappointment bias in pragmatic trials. On cohort enrollment, broad informed consent for randomization is asked, after which cohort participants can be randomized to interventions or serve as controls without further notification. We evaluated patients’ recollection, understanding, and acceptance of broad consent in a clinical oncology setting. Methods: We surveyed 610 patients with cancer participating in ongoing TwiCs; 482 patients (79%) responded, of which 312 patients shortly after cohor... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2021 |
Schlagwörter: | Cohort studies / Informed consent / Randomized controlled trials / Study design / Trials within Cohorts / Patient Participation/psychology / Humans / Middle Aged / Male / Colorectal Neoplasms/therapy / Patient Selection / Netherlands / Aged / 80 and over / Adult / Female / Surveys and Questionnaires / Biomedical Research/standards / Bone Neoplasms/therapy / Neoplasm Metastasis/therapy / Medical Oncology/standards / Breast Neoplasms/therapy / Research Design / Clinical Trials as Topic/standards / Practice Guidelines as Topic / Epidemiology / Journal Article / Review |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27612643 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/441548 |