Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands
BACKGROUND: Procalcitonin (PCT) testing can help in safely reducing antibiotic treatment duration in intensive care patients with sepsis. However, the cost-effectiveness of such PCT guidance is not yet known. METHODS: A trial-based analysis was performed to estimate the cost-effectiveness of PCT guidance compared with standard of care (without PCT guidance). Patient-level data were used from the SAPS trial in which 1546 patients were randomised. This trial was performed in the Netherlands, which is a country with, on average, low antibiotic use and a short duration of hospital stay. As quality... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2018 |
Schlagwörter: | Adult / Anti-Bacterial Agents/administration & dosage / Biomarkers/analysis / Cost-Benefit Analysis/standards / Critical Illness/economics / Female / Hospital Mortality / Humans / Intensive Care Units/economics / Length of Stay/economics / Male / Netherlands / Procalcitonin/analysis / Prospective Studies / Sepsis/blood / Time Factors / Journal Article / Multicenter Study / Randomized Controlled Trial |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27611037 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/372977 |