Case-only designs for studying the association of antidepressants and hip or femur fracture

Purpose: The purpose of this study is to evaluate the performance and validity of the case-crossover (CCO) and self-controlled case-series (SCCS) designs when studying the association between hip/femur fracture (HF) and antidepressant (AD) use in general practitioner databases. In addition, comparability with cohort and case-control designs is discussed. Methods: Adult patients with HF and who received an AD prescription during 2001-2009 were identified from UK's The Health Improvement Network (THIN) and the Dutch Mondriaan databases. AD exposure was classified into current, recent and past/no... Mehr ...

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Verfasser: De Groot, Mark C. H.
Candore, Gianmario
Uddin, Jamal
Souverein, Patrick
Ali, M. Sanni
Belitser, S.
Huerta, Consuelo
Groenwold, Rolf H. H.
Alvarez, Yolanda
Slattery, Jim
Korevaar, Joke
Hoes, Arno W.
Roes, Kit C. B.
de Boer, Anthonius
Douglas, Ian J.
Schlienger, Raymond G.
Reynolds, Robert
Klungel, Olaf H.
Gardarsdottir, Helga
Dokumenttyp: Artikel
Erscheinungsdatum: 2016
Schlagwörter: Antidepressant / Case-crossover / Case-only design / Hip/femur fracture / Methodology / Pharmacoepidemiology / Self-controlled case series / antidepressant agent / serotonin uptake inhibitor / tricyclic antidepressant agent / adult / age / aged / article / case control study / case study / cohort analysis / confidence interval / correlation analysis / data base / drug exposure / electronic medical record / evaluation study / female / femur fracture / hip fracture / human / incidence / logistic regression analysis / major clinical study / male / multicenter study / Netherlands / outcome assessment / Poisson distribution / priority journal / regression analysis / risk assessment / study design / United Kingdom / validity / Taverne
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27610537
Datenquelle: BASE; Originalkatalog
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Link(s) : https://dspace.library.uu.nl/handle/1874/336989