Clinical Surveillance vs. Anticoagulation For low-risk patiEnts with isolated SubSegmental Pulmonary Embolism: protocol for a multicentre randomised placebo-controlled non-inferiority trial (SAFE-SSPE)
Introduction: The clinical significance of subsegmental pulmonary embolism (SSPE) is currently unclear. Although growing evidence from observational studies suggests that withholding anticoagulant treatment may be a safe option in selected patients with isolated SSPE, most patients with this condition receive anticoagulant treatment, which is associated with a 90-day risk of recurrent venous thromboembolism (VTE) of 0.8% and major bleeding of up to 5%. Given the ongoing controversy concerning the risk-benefit ratio of anticoagulation for isolated SSPE and the lack of evidence from randomised-c... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2020 |
Schlagwörter: | info:eu-repo/classification/ddc/616 / Anticoagulation / Randomised clinical trialx / Subsegmental pulmonary embolism / Adult / Anticoagulants / adverse effects / Canada / Double-Blind Method / Humans / Netherlands / Pulmonary Embolism / drug therapy / Quality of Life / Randomized Controlled Trials as Topic / Switzerland / Venous Thromboembolism / drug therapy / Venous Thromboembolism / prevention & control |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27606100 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://archive-ouverte.unige.ch/unige:161628 |