No outcome disparities in patients with diffuse large B-cell lymphoma and a low socioeconomic status

Introduction: In patients with diffuse large B-cell lymphoma (DLBCL) socioeconomic status (SES) is associated with outcome in several population-based studies. The aim of this study was to further investigate the existence of disparities in treatment and survival. Methods: A population-based cohort study was performed including 343 consecutive patients with DLBCL, diagnosed between 2005 and 2012, in the North-west of the Netherlands. SES was based on the socioeconomic position within the Netherlands by use of postal code and categorized as low, intermediate or high. With multivariable logistic... Mehr ...

Verfasser: Boslooper, Karin
Hoogendoorn, Mels
van Roon, Eric N.
Kibbelaar, Robby E.
Storm, Huib
Hovenga, Sjoerd
Woolthuis, Gerhard
van Rees, Bas P.
Klijs, Bart
Veeger, Nic J. G. M.
Kluin-Nelemans, Hanneke C.
de Bock, Geertruida H.
Dokumenttyp: Artikel
Erscheinungsdatum: 2017
Reihe/Periodikum: Boslooper , K , Hoogendoorn , M , van Roon , E N , Kibbelaar , R E , Storm , H , Hovenga , S , Woolthuis , G , van Rees , B P , Klijs , B , Veeger , N J G M , Kluin-Nelemans , H C & de Bock , G H 2017 , ' No outcome disparities in patients with diffuse large B-cell lymphoma and a low socioeconomic status ' , Cancer epidemiology , vol. 48 , pp. 110-116 . https://doi.org/10.1016/j.canep.2017.04.009
Schlagwörter: DLBCL / Socioeconomic status / Population-based / NON-HODGKIN-LYMPHOMA / POPULATION-BASED COHORT / ELDERLY-PATIENTS / SURVIVAL / CANCER / INEQUALITIES / NETHERLANDS / MORTALITY / DENMARK / IMPACT
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27600407
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://hdl.handle.net/11370/3a61c49e-d9b1-420e-81ab-cb6e08492e00

Introduction: In patients with diffuse large B-cell lymphoma (DLBCL) socioeconomic status (SES) is associated with outcome in several population-based studies. The aim of this study was to further investigate the existence of disparities in treatment and survival. Methods: A population-based cohort study was performed including 343 consecutive patients with DLBCL, diagnosed between 2005 and 2012, in the North-west of the Netherlands. SES was based on the socioeconomic position within the Netherlands by use of postal code and categorized as low, intermediate or high. With multivariable logistic regression and Cox proportional hazard models the association between SES and respectively treatment and overall survival (OS) was evaluated. Results: Two-third of patients was positioned in low SES. Irrespective of SES an equal proportion of patients received standard immunochemotherapy. SES was not a significant risk indicator for OS (intermediate versus low SES: hazard ratio (HR) 1.31 (95% CI 0.78-2.18); high versus low SES: HR 0.83 (95% CI 0.48-1.46)). The mortality risk remained significantly increased with higher age, advanced performance status, elevated LDH and presence of comorbidity. Conclusion: Within the setting of free access to health care, in this cohort of patients with DLBCL no disparities in treatment and survival were seen in those with lower SES. (C) 2017 Elsevier Ltd. All rights reserved.