Glycemic load, glycemic index, and pancreatic cancer risk in the Netherlands Cohort Study

BACKGROUND: Recent studies of pancreatic cancer suggest a role for hyperinsulinemia in carcinogenesis. Because insulin is secreted in response to elevated blood glucose concentrations, dietary factors that increase these concentrations may be important in pancreatic carcinogenesis. OBJECTIVE: The objective was to examine prospectively the relation between pancreatic cancer risk and dietary glycemic load (GL), overall glycemic index (GI), and intake of total carbohydrates and mono- and disaccharides. DESIGN: The Netherlands Cohort Study consisted of 120,852 men and women who completed a baselin... Mehr ...