Multicenter analyses demonstrate significant clinical effects of minor Histocompatibility Antigens on GvHD and GvL after HLA-matched related and unrelated Hematopoietic stem cell transplantation
The effect of minor H antigen mismatching on the occurrence of graft-versus-host disease (GvHD) and graft-versus-leukemia (GvL) after HLA-matched hematopoietic stem cell transplantation (HSCT) has mainly been demonstrated in single-center studies. Yet, the International Histocompatibility and Immunogenetics Workshops (IHIW) provide a collaborative platform to execute crucial large studies. In collaboration with 20 laboratories of the IHIW, the roles of 10 autosomal and 10 Y chromosome-encoded minor H antigens were investigated on GvHD and relapse incidence in 639 HLA-identical related donor (I... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2013 |
Schlagwörter: | Knowmad Institut / Netherlands / Transplantation / Hematology / European Commission |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27591270 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://www.openaccessrepository.it/record/142835 |