In both academic literature and flood risk management practices, it is argued that governance initiatives are needed to enhance the flood resilience of urban agglomerations. Multiple levels of governance will be involved in this activity. However, thus far, the literature has hardly addressed what mechanisms are required to coordinate the different levels of managing urban flood resilience, and what factors account for these mechanisms. Our aim is to address this knowledge gap. Here, we examine six in-depth case studies undertaken in urban agglomerations in different European countries: Dordrecht, the Netherlands; Hull, UK; Geraardsbergen, Belgium; Karlstad, Sweden; Wrocław, Poland; and Nice, France. The case studies reveal the ways in which multiple levels of governance are involved in managing urban flood resilience. Coordination among governance levels is achieved by proactive policy entrepreneurs, the use of bridging concepts, clear rules, and the provision of resources. These mechanisms seem to be universally applicable, but their characteristics appear to be highly dependent on more general institutional, economic, geographical, and cultural contextual factors.