Identification of Risk Factors for Chronic Q Fever, the Netherlands

Since 2007, the Netherlands has experienced a large Q fever outbreak. To identify and quantify risk factors for development of chronic Q fever after Coxiella burnetii infection, we performed a case–control study. Comorbidity, cardiovascular risk factors, medications, and demographic characteristics from 105 patients with proven (n = 44), probable (n = 28), or possible (n = 33) chronic Q fever were compared with 201 patients who had acute Q fever in 2009 but in whom chronic Q fever did not develop (controls). Independent risk factors for development of proven chronic Q fever were valvular surge... Mehr ...

Verfasser: Linda M. Kampschreur
Sandra Dekker
Julia C.J.P. Hagenaars
Peter J. Lestrade
Nicole H.M. Renders
Monique G.L. de Jager-Leclercq
Mirjam H.A. Hermans
Cornelis A.R. Groot
Rolf H.H. Groenwold
Andy I.M. Hoepelman
Peter C. Wever
Jan Jelrik Oosterheert
Dokumenttyp: Artikel
Erscheinungsdatum: 2012
Reihe/Periodikum: Emerging Infectious Diseases, Vol 18, Iss 4, Pp 563-570 (2012)
Verlag/Hrsg.: Centers for Disease Control and Prevention
Schlagwörter: Q fever / Coxiella burnetii / chronic Q fever / risk factors / case–control study / acute Q fever / Medicine / R / Infectious and parasitic diseases / RC109-216
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27582164
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.3201/eid1804.111478

Since 2007, the Netherlands has experienced a large Q fever outbreak. To identify and quantify risk factors for development of chronic Q fever after Coxiella burnetii infection, we performed a case–control study. Comorbidity, cardiovascular risk factors, medications, and demographic characteristics from 105 patients with proven (n = 44), probable (n = 28), or possible (n = 33) chronic Q fever were compared with 201 patients who had acute Q fever in 2009 but in whom chronic Q fever did not develop (controls). Independent risk factors for development of proven chronic Q fever were valvular surgery, vascular prosthesis, aneurysm, renal insufficiency, and older age.