Genetic Basis for Immunological Aberrations in Poliovirus Sabin Serotype 3 Strains Imported in The Netherlands
ABSTRACT During the characterization of poliovirus type 3 strains imported in The Netherlands, Sabin serotype 3 strains that reacted with both specific antisera against Sabin-like (vaccine) and non-Sabin-like (wild-type) strains by the intratypic strain differentiation assay have been found. The present study was done to determine the pathogenic potential of these virus strains for humans. Characterization of these so-called double-reactive strains with neutralizing monoclonal antibodies (MAbs) against the major antigenic sites of serotype 3 Sabin virus led to the identification of two groups... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 1999 |
Reihe/Periodikum: | Journal of Clinical Microbiology ; volume 37, issue 8, page 2393-2398 ; ISSN 0095-1137 1098-660X |
Verlag/Hrsg.: |
American Society for Microbiology
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Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27579251 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1128/jcm.37.8.2393-2398.1999 |