Hypertension and low HDL cholesterol were associated with reduced kidney function across the age spectrum: a collaborative study

PurposeTo determine if the associations among established risk factors and reduced kidney function vary by age.MethodsWe pooled cross-sectional data from 14,788 nondiabetics aged 40 to 100 years in 4 studies: Cardiovascular Health Study, Health, Aging, and Body Composition Study, Multi-Ethnic Study of Atherosclerosis, and Prevention of Renal and Vascular End-Stage Disease cohort.ResultsHypertension and low high-density lipoprotein (HDL) cholesterol were associated with reduced cystatin C-based estimated glomerular filtration rate (eGFR) across the age spectrum. In adjusted analyses, hypertensi... Mehr ...