Clinical and Molecular Characteristics of Extended-Spectrum- β-Lactamase-Producing Escherichia coli Causing Bacteremia in the Rotterdam Area, Netherlands

ABSTRACT We investigated the clinical and molecular characteristics of bacteremia caused by extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli over a 2-year period (2008 to 2009) in the Rotterdam region (including 1 teaching hospital and 2 community hospitals) of Netherlands. The majority of patients presented with community onset urinary and intra-abdominal infections, with an increase in prevalence during 2009. The majority of E. coli isolates produced CTX-M-15, and 4 sequence types (ST38, ST131, ST405, and ST648) predominated. There were significant differences in clinical and... Mehr ...

Verfasser: van der Bij, Akke K.
Peirano, Gisele
Goessens, Wil H. F.
van der Vorm, Eric R.
van Westreenen, M.
Pitout, Johann D. D.
Dokumenttyp: Artikel
Erscheinungsdatum: 2011
Reihe/Periodikum: Antimicrobial Agents and Chemotherapy ; volume 55, issue 7, page 3576-3578 ; ISSN 0066-4804 1098-6596
Verlag/Hrsg.: American Society for Microbiology
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27568182
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://dx.doi.org/10.1128/aac.00074-11

ABSTRACT We investigated the clinical and molecular characteristics of bacteremia caused by extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli over a 2-year period (2008 to 2009) in the Rotterdam region (including 1 teaching hospital and 2 community hospitals) of Netherlands. The majority of patients presented with community onset urinary and intra-abdominal infections, with an increase in prevalence during 2009. The majority of E. coli isolates produced CTX-M-15, and 4 sequence types (ST38, ST131, ST405, and ST648) predominated. There were significant differences in clinical and molecular characteristics between the 2 community hospitals.