Living Labs are seen as open innovation systems adopting a user-centered approach (Schuurman et al., 2012), but academic research into the methodological elements is still lacking, resulting in a diversity of definitions, approaches and characteristics (Følstad, 2008; Almirall & Wareham, 2011; Leminen & Westerlund, 2012). Within this paper, based upon a literature review, we propose a conceptual model of a Living Lab constellation, facilitated by a given material and immaterial infrastructure, which facilitates Living Lab-cases that follow a quasi-experimental design. Through an in-depth case study analysis of the LeYLab Living Lab constellation and six separate cases running in the Living Lab, we assess the applicability of our model and abstract some general lessons learned. Our study demonstrates the potential of infrastructure-driven Living Labs, but also that the allignment of external utilizers with this infrastructure can be problematic.