The castle of Montreuil-Bellay was rebuilt by Guillaume d’Harcourt († 1487) and his wife Yolande de Laval († 1487). It contains in one of the chapels a rare testimony of murals dating from the last quarter of the fifteenth century in the Loire Valley, in France. Based on a widespread iconography, images however respond to specific expectations of the owners. Several complementary readings can be made in the representation of the six saints painted in the chapel. Individual devotions combine collective concerns of several members of the Harcourt and Laval families. Also, this short introduction on the murals also leads us to take a new look at the painter in charge of it. The artist, who was familiar with Flemish painting innovations during the fifteenth century. He probably can be identified with Coppin Delf. From an artistic standpoint, the murals of Montreuil-Bellay put on display an entanglement of different influences and iconographic sources. Indeed, they emphasize the extent and complexity in artistic transfers away from political divisions or distant geographical areas.