HPV16 whole genome minority variants in persistent infections from young Dutch women
Background: Chronic infections by one of the oncogenic human papillomaviruses (HPVs) are responsible for near 5% of the global cancer burden and HPV16 is the type most often found in cancers. HPV genomes display unexpected levels of variation when deep-sequenced. Minor nucleotide variations (MNVs) may reveal HPV genomic instability and HPV-related carcinogenic transformation of host cells. Objectives: The objective of this study was to investigate HPV16 genome variation at the minor variant level on persisting HPV16 cervical infections from a population of young Dutch women. Study design: 15 H... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2019 |
Reihe/Periodikum: | Lagström , S , van der Weele , P , Rounge , T B , Christiansen , I K , King , A J & Ambur , O H 2019 , ' HPV16 whole genome minority variants in persistent infections from young Dutch women ' , Journal of Clinical Virology , vol. 119 , pp. 24-30 . https://doi.org/10.1016/j.jcv.2019.08.003 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27464752 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.vumc.nl/en/publications/32ac6baa-de0b-4dab-891b-a5f65d75e77a |