Long-Term Natural Course of Small Nonfunctional Pancreatic Neuroendocrine Tumors in MEN1-Results From the Dutch MEN1 Study Group

Background: Pancreatic neuroendocrine tumors (pNETs) are highly prevalent in patients with multiple endocrine neoplasia type 1 (MEN1), and metastatic disease is an important cause of MEN1-related mortality. Especially small nonfunctional (NF) pNETs pose a challenge to the treating physician and more information is needed regarding their natural course. We assessed long-term natural history of small NF-pNETs and its modifiers in the Dutch MEN1 population. Patients and Methods: Retrospective longitudinal observational cohort study of patients with small (<2 cm) NF-pNETs from the Dutch nationa... Mehr ...

Verfasser: Pieterman, Carolina R.C.
de Laat, Joanne M.
Twisk, Jos W.R.
van Leeuwaarde, Rachel S.
de Herder, Wouter W.
Dreijerink, Koen M.A.
Hermus, Ad R.M.M.
Dekkers, Olaf M.
van der Horst-Schrivers, Anouk N.A.
Drent, Madeleine L.
Bisschop, Peter H.
Havekes, Bastiaan
Borel Rinkes, Inne H.M.
Vriens, Menno R.
Valk, Gerlof D.
Dokumenttyp: Artikel
Erscheinungsdatum: 2017
Reihe/Periodikum: Pieterman , C R C , de Laat , J M , Twisk , J W R , van Leeuwaarde , R S , de Herder , W W , Dreijerink , K M A , Hermus , A R M M , Dekkers , O M , van der Horst-Schrivers , A N A , Drent , M L , Bisschop , P H , Havekes , B , Borel Rinkes , I H M , Vriens , M R & Valk , G D 2017 , ' Long-Term Natural Course of Small Nonfunctional Pancreatic Neuroendocrine Tumors in MEN1-Results From the Dutch MEN1 Study Group ' , Journal of Clinical Endocrinology and Metabolism , vol. 102 , no. 10 , pp. 3795-3805 . https://doi.org/10.1210/jc.2017-00372
Schlagwörter: Adult / Disease Progression / Female / Humans / Longitudinal Studies / Male / Middle Aged / Multiple Endocrine Neoplasia Type 1 / Neuroendocrine Tumors / Pancreatic Neoplasms / Prognosis / Retrospective Studies / Time Factors / Tumor Burden / Young Adult / Journal Article / Observational Study / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27463391
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/36cfdec7-86e1-475b-b477-081b1b33e661