Introduction: The objective of this study was to identify genetic variants that are associated with adult leisure time exercise behavior using genome-wide association (GWA) in two independent samples. Methods: Exercise behavior was measured in 1644 unrelated Dutch and 978 unrelated American adults of European ancestry with detailed questions about type, frequency, and duration of exercise. Individuals were classified into regular exercisers or nonexercisers using a threshold of 4 MET•h (metabolic equivalents-hours per week). GWA analyses of ∼1.6 million observed and imputed Single Nucleotide P... Mehr ...
| Verfasser: |
De Moor, Marleen H.M.
Liu, Yong Jun
Boomsma, Dorret I.
Li, Jian
Hamilton, James J.
Hottenga, Jouke Jan
Levy, Shawn
Liu, Xiao Gang
Pei, Yu Fang
Posthuma, Danielle
Recker, Robert R.
Sullivan, Patrick F.
Wang, Liang
Willemsen, Gonneke
Yan, Han
De Geus, Eco J.C.
Deng, Hong Wen |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2009 |
| Reihe/Periodikum: |
De Moor , M H M , Liu , Y J , Boomsma , D I , Li , J , Hamilton , J J , Hottenga , J J , Levy , S , Liu , X G , Pei , Y F , Posthuma , D , Recker , R R , Sullivan , P F , Wang , L , Willemsen , G , Yan , H , De Geus , E J C & Deng , H W 2009 , ' Genome-wide association study of exercise behavior in dutch and american adults ' , Medicine and Science in Sports and Exercise , vol. 41 , no. 10 , pp. 1887-1895 . https://doi.org/10.1249/MSS.0b013e3181a2f646 |
| Schlagwörter: |
Genetics
/ Genotype imputation
/ Physical activity
/ Sports participation
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-27463380 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/31f03db8-9535-42a9-bc9d-92ba0a4e2a48 |
