FAM19A4/miR124-2 methylation analysis as a triage test for HPV-positive women: cross-sectional and longitudinal data from a Dutch screening cohort
Objectives: The aim was to evaluate the cross-sectional and long-term triage performance of FAM19A4/miR124-2 methylation analysis in human papillomavirus (HPV)-based cervical screening. Methods: We conducted a post hoc analysis within a Dutch population-based HPV-positive study cohort of women aged 30–60 years (n = 979). Cross-sectional cervical intraepithelial neoplasia (CIN) 3+ sensitivity, specificity, positive predictive value and negative predictive value as well as cumulative CIN3+ or cervical cancer risks after 9 and 14 years were compared for three baseline triage strategies: (1) cytol... Mehr ...
Verfasser: |
Vink, FJ
Lissenberg-Witte, BI
Meijer, C
Berkhof, J
van Kemenade, Folkert
Siebers, AG
Steenbergen, RDM
Bleeker, MCG
Heideman, DAM |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2021 |
Reihe/Periodikum: |
Vink , FJ , Lissenberg-Witte , BI , Meijer , C , Berkhof , J , van Kemenade , F , Siebers , AG , Steenbergen , RDM , Bleeker , MCG & Heideman , DAM 2021 , ' FAM19A4/miR124-2 methylation analysis as a triage test for HPV-positive women: cross-sectional and longitudinal data from a Dutch screening cohort ' , Clinical Microbiology and Infection , vol. 27 , no. 1 , pp. 125.e1-125.e6 . https://doi.org/10.1016/j.cmi.2020.03.018 |
Schlagwörter: |
/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ SDG 3 - Good Health and Well-being |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-27461029 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://pure.eur.nl/en/publications/70fb2f44-14b4-4bdf-9830-06e6136f79a4 |