Baseline dimensional psychopathology and future mood disorder onset:findings from the Dutch Bipolar Offspring Study

Objective: To identify the early signs of mood disorder development, specifically bipolar disorder (BD), in a population at familial risk for BD.Method: The sample included 107 Dutch adolescent bipolar offspring (age 12-21) followed into adulthood (age 22-32). Lifetime DSM-IV axis I diagnoses were examined at baseline, 1-, 5-, and 12-year follow-up. Symptoms were assessed at baseline on a 3-point Likert scale at baseline with the K-SADS-PL and were analyzed using symptom and sum scores. As observed in previous studies, BD typically starts with other mood disorders. Therefore, the sample was st... Mehr ...