De-escalation of axillary surgery in breast cancer patients treated in the neoadjuvant setting: a Dutch population-based study

Purpose: An overall trend is observed towards de-escalation of axillary surgery in patients with breast cancer. The objective of this study was to evaluate this trend in patients treated with neoadjuvant systemic therapy (NST). Methods: Patients with cT1-4N0-3 breast cancer treated with NST (2006–2016) were selected from the Netherlands Cancer Registry. Patients were classified by clinical node status (cN) and type of axillary surgery. Uni- and multivariable logistic regression analyses were performed to determine the clinicopathological factors associated with performing ALND in cN+ patients.... Mehr ...

Volltext
Verfasser: Simons, J M
Koppert, L B
Luiten, E J T
van der Pol, C C
Samiei, S
de Wilt, J H W
Siesling, S
Smidt, M L
Dokumenttyp: Artikel
Erscheinungsdatum: 2020
Schlagwörter: Adolescent / Adult / Aged / 80 and over / Antineoplastic Combined Chemotherapy Protocols/therapeutic use / Axilla / Breast Neoplasms/drug therapy / Carcinoma / Ductal / Breast/drug therapy / Lobular/drug therapy / Combined Modality Therapy / Female / Follow-Up Studies / Humans / Lymph Node Excision/statistics & numerical data / Mastectomy/statistics & numerical data / Middle Aged / Neoadjuvant Therapy/methods / Netherlands/epidemiology / Prognosis / Receptor / ErbB-2/metabolism / Receptors / Estrogen/metabolism / Progesterone/metabolism / Sentinel Lymph Node Biopsy/statistics & numerical data / Survival Rate / Withholding Treatment / Young Adult / Axillary staging / Node positive / Breast cancer / Marked node / Sentinel lymph node biopsy / Axillary lymph node dissection / Oncology / Cancer Research / Journal Article
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27457670
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://dspace.library.uu.nl/handle/1874/441465