Metabolic syndrome parameters, determinants, and biomarkers in adult survivors of childhood cancer: Protocol for the Dutch childhood cancer survivor study on metabolic syndrome (Dutch LATER METS)

BACKGROUND: Potential late effects of treatment for childhood cancer include adiposity, insulin resistance, dyslipidemia, and hypertension. These risk factors cluster together as metabolic syndrome and increase the risk for development of diabetes mellitus and cardio- and cerebrovascular disease. Knowledge on risk factors, timely diagnosis, and preventive strategies is of importance to prevent cardio- and cerebrovascular complications and improve quality of life. Currently, no national cohort studies on the prevalence and determinants of metabolic syndrome in childhood cancer survivors, includ... Mehr ...