Background Economic evaluation of health-care interventions often involves the use of quality adjusted life years (QALYs) to capture the benefit of different interventions. The quality adjustment weight of the QALY is often generated using an existing generic preference-based measure such as the EQ5D or SF-6D, but these measures were developed for adults and are not intended for use in children. The Child Health Utility 9D (CHU-9D) is a generic paediatric preference-based measure that was specifically developed and worded for use in paediatric populations. Value sets exist for the UK and Australia, enabling the measure to generate QALYs using population-specific value sets for those countries. This aim of this study was to generate a Dutch value set for the CHU-9D, a paediatric preference-based measure of quality of life that can be used to generate quality adjusted life years (QALYs).