HLA association in MOG-IgG- and AQP4-IgG-related disorders of the CNS in the Dutch population

OBJECTIVE: To investigate the possible human leukocyte antigen (HLA) association of both myelin oligodendrocyte glycoprotein (MOG-IgG)-associated diseases (MOGAD) and aquaporin-4 antibody (AQP4-IgG)-positive neuromyelitis optica spectrum disorders (NMOSDs) in the Dutch population with European ancestry to clarify similarities or differences in the immunogenetic background of both diseases. METHODS: Blood samples from patients in the Dutch national MS/NMOSD expert clinic were tested for MOG-IgG and AQP4-IgG using a cell-based assay. HLA Class I and II genotyping was performed in 43 MOG-IgG-sero... Mehr ...

Verfasser: Bruijstens, A.L. (Arlette L.)
Wong, Y.Y.M. (Yu Yi)
Pelt - Gravesteijn, E.D. (Daniëlle) van
van der Linden, P.J.E. (Pieter J E)
Haasnoot, G.W. (Geert)
Hintzen, R.Q. (Rogier)
Claas, F.H.J. (Frans)
Neuteboom, R.F. (Rinze)
Wokke, B.H.A. (Beatrijs H A)
Dokumenttyp: Artikel
Erscheinungsdatum: 2020
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27452765
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://repub.eur.nl/pub/125805