The relationship between leptin, gonadotropic hormones, and body composition during puberty in a Dutch children cohort

Objective To investigate the relationship between leptin concentrations, gonadotropic hormone concentrations, and body composition during puberty in a Dutch children cohort. Design In a cohort of 98 children, we determined anthropometric measurements, body composition, and concentrations of leptin, FSH, and LH. Results Sex differences were observed from Tanner stage 1 onwards in weight, body fat percentage, and leptin/fat mass ratio. In boys and girls, the relationship between leptin concentrations and FM was weaker at Tanner stage 2 ( R 2 =0.33 and R 2 =0.39; P <0.001), 3 ( R 2 =0.27 and R... Mehr ...