Prostate cancer susceptibility genes on 8p21-23 in a Dutch population

Background:Prostate cancer is the most commonly diagnosed cancer in men and the United States. Numerous studies have indicated genetics to have role in the aetiology of this disease; as much as 42% of the risk may be explained by heritable factors. Genome-wide association studies have association between prostate cancer and chromosome 8p21-23. In this analysed eight microsatellite (MS) markers in that region in order to previous results and narrow down the location of candidate prostate genes.Methods:292 cases and 278 controls were selected from the Cohort Study (NLCS). The following MSs were... Mehr ...