Prognostic factors and survival in MEN1 patients with gastrinomas:Results from the DutchMEN study group (DMSG)

Background and objectives Gastrinomas are the most prevalent functioning neuroendocrine tumors (NET) in multiple endocrine neoplasia type 1 (MEN1). Guidelines suggest medical therapy in most patients, but surgery may be considered in a subgroup. Currently, factors to guide management are necessary. This population-based cohort study assessed prognostic factors of survival in patients with MEN1-related gastrinomas. Methods Patients with MEN1 having gastrinomas were identified in the Dutch MEN1 database from 1990 to 2014 based on fasting serum gastrin (FSG) levels and/or pathology. Predictors of... Mehr ...

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Verfasser: van Beek, Dirk-Jan
Nell, Sjoerd
Pieterman, Carolina R. C.
de Herder, Wouter W.
van de Ven, Annenienke C.
Dekkers, Olaf M.
van der Horst-Schrivers, Anouk N.
Drent, Madeleine L.
Bisschop, Peter H.
Havekes, Bas
Rinkes, Inne H. M. Borel
Vriens, Menno R.
Valk, Gerlof D.
Dokumenttyp: Artikel
Erscheinungsdatum: 2019
Reihe/Periodikum: van Beek , D-J , Nell , S , Pieterman , C R C , de Herder , W W , van de Ven , A C , Dekkers , O M , van der Horst-Schrivers , A N , Drent , M L , Bisschop , P H , Havekes , B , Rinkes , I H M B , Vriens , M R & Valk , G D 2019 , ' Prognostic factors and survival in MEN1 patients with gastrinomas : Results from the DutchMEN study group (DMSG) ' , Journal of Surgical Oncology , vol. 120 , no. 6 , pp. 966-975 . https://doi.org/10.1002/jso.25667
Schlagwörter: multiple endocrine neoplasia type 1 / neuroendocrine tumor / oncology / Zollinger-Ellison syndrome / ENDOCRINE NEOPLASIA TYPE-1 / ZOLLINGER-ELLISON-SYNDROME / PANCREATIC NEUROENDOCRINE TUMORS / NATURAL-HISTORY / GUIDELINES / MANAGEMENT / DIAGNOSIS / SURGERY
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27439911
Datenquelle: BASE; Originalkatalog
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Link(s) : https://cris.maastrichtuniversity.nl/en/publications/5875072a-269e-4e63-a6b2-23d32f363320