Correction to: Genetics in Medicine 2022; https://doi.org/10.1016/j.gim.2022.07.009, published online 2 September 2022. In the article “Expanding the genetic and phenotypic spectrum of ACTA2-related vasculopathies in a Dutch cohort” (Genet Med 2022;24:2112-2122), the following updates were made. On page 2114 (Molecular studies section), the sentence “Functional assay for the splice variant p.[Ala206Gly,Glu207_Ile269del] showed no aberrant splicing and an equal presence of both alleles.” was changed to “Functional assay for the splice variant c.808G>A showed aberrant splicing and an (in frame) exon 7 mRNA deletion, with equal presence of both alleles (Table 2).” On page 2115 (Table 2), in the “Protein Change” column “p.[Ala206Gly,Glu207_Ile269del]” was changed to “p.[Gly270Arg] e and p.[p.Ala206_Ile269del] f .” In the list of footnotes at the bottom of Table 2, “ e r.808g>a, both outcomes of the variant c.808G>A” and “f r.617_808del, both outcomes of the variant c.808G>A” were added to the Table 2 footnote list. On page 2117, Table 4 table body (under column ACTA2 Variant) “p.[Ala206Gly,Glu207_Ile269del]” was changed to “p.[Gly270Arg], p.[Ala206_Ile269del]” and “p.[Ala206Gly,Glu207_Ile269del]” was changed to “p.[Gly270Arg], p.[Ala206_Ile269del]” (rows 10 and 13). On page 2119 (right-hand column, second paragraph), the sentence “The other 2 variants in our study associated with iris flocculi were novel, namely p.[Ala206Gly,Glu207_Ile269del] and p.(Thr162Asn).” was changed to “The other 2 variants in our study associated with iris flocculi were novel, namely p.[Gly270Arg], p.[Ala206_Ile269del] and p.(Thr162Asn).” The article has been corrected online and can be accessed at https://doi.org/10.1016/j.gim.2022.07.009.