Association of P2Y(2) receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients
The P2Y(2) receptor is a G-protein-coupled receptor with adenosine 5'-triphosphate (and UTP) as natural ligands. It is thought to be involved in bone physiology in an anti-osteogenic manner. As several non-synonymous single nucleotide polymorphisms (SNPs) have been identified within the P2Y(2) receptor gene in humans, we examined associations between genetic variations in the P2Y(2) receptor gene and bone mineral density (BMD) (i.e., osteoporosis risk), in a cohort of fracture patients. Six hundred and ninety women and 231 men aged a parts per thousand yen50 years, visiting an osteoporosis out... Mehr ...
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| Dokumenttyp: | Artikel |
| Erscheinungsdatum: | 2013 |
| Reihe/Periodikum: | Wesselius , A , Bours , M J L , Henriksen , Z , Syberg , S , Petersen , S , Schwarz , P , Jorgensen , N R , van Helden , S & Dagnelie , P C 2013 , ' Association of P2Y(2) receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients ' , Purinergic Signalling , vol. 9 , no. 1 , pp. 41-49 . https://doi.org/10.1007/s11302-012-9326-3 |
| Schlagwörter: | P2Y(2) receptor / Osteoporosis / Bone mineral density / Polymorphisms |
| Sprache: | Englisch |
| Permalink: | https://search.fid-benelux.de/Record/base-27439718 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://cris.maastrichtuniversity.nl/en/publications/248a937c-ea49-4715-8cae-224452de2d6a |
