Identification of a Novel Genomic Island Associated with vanD -Type Vancomycin Resistance in Six Dutch Vancomycin-Resistant Enterococcus faecium Isolates
ABSTRACT Genomic comparison of the first six Dutch vanD -type vancomycin-resistant Enterococcus faecium (VRE) isolates with four vanD gene clusters from other enterococcal species and anaerobic gut commensals revealed that the vanD gene cluster was located on a genomic island of variable size. Phylogenetic inferences revealed that the Dutch VRE isolates were genetically not closely related and that genetic variation of the vanD -containing genomic island was not species specific, suggesting that this island is transferred horizontally between enterococci and anaerobic gut commensals.
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2018 |
Reihe/Periodikum: | Antimicrobial Agents and Chemotherapy ; volume 62, issue 3 ; ISSN 0066-4804 1098-6596 |
Verlag/Hrsg.: |
American Society for Microbiology
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Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27408278 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1128/aac.01793-17 |