The STIB score: a simple clinical test to predict clopidogrel resistance.

BACKGROUND: High platelet reactivity (HPR) to clopidogrel is associated with an increased risk of ischaemic complications during and after coronary interventions and concerns up to 50% of patients undergoing PCI. AIM OF THE STUDY: The aim of the study was to identify patients with HPR to clopidogrel using bedside clinical information obtained in the Stent Thrombosis In Belgium (STIB) trial. METHODS: Data on platelet reactivity using the VerifyNow® point-of-care assay were obtained in 844 patients undergoing PCI for stable coronary artery disease 12 to 24 hours after a 600-mg loading dose of c... Mehr ...

Volltext
Verfasser: Legrand, Delphine
Barbato, Emanuele
Chenu, Patrick
Magne, Julien
Vrolix, Mathias
Wijns, William
Legrand, Victor
STIB investigators
Dokumenttyp: Artikel
Erscheinungsdatum: 2015
Verlag/Hrsg.: Peeters
Schlagwörter: Aged / Decision Support Techniques / Diabetes Complications / Drug Resistance / Female / Hemoglobins / Humans / Logistic Models / Male / Middle Aged / Multivariate Analysis / Angina / Stable / Obesity / Odds Ratio / Platelet Aggregation / Platelet Aggregation Inhibitors / Platelet Function Tests / Point-of-Care Testing / Predictive Value of Tests / Prospective Studies / Purinergic P2Y Receptor Antagonists / Receptors / Purinergic P2Y12 / Angioplasty / Balloon / Coronary / Risk Factors / Ticlopidine / Time Factors / Treatment Outcome / Belgium / Biomarkers / Blood Platelets / Body Mass Index / Chi-Square Distribution / Comorbidity / Bleeding / Clopidogrel resistance / Coronary disease / Ischaemic events / Verifynow®
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27369375
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://hdl.handle.net/2078.1/176260