Case Report: Hyperreactive Malarial Splenomegaly Syndrome Diagnosed with Loop-Mediated Isothermal Amplification and Treated with Artemisinin-Based Combination Therapy.
Hyperreactive malarial splenomegaly syndrome (HMSS) is a rare cause of splenomegaly in the Western world. Hyperreactive malarial splenomegaly syndrome is caused by an aberrant immunological response to chronic malaria exposure in endemic areas. Revised Fakunle's criteria may be helpful for diagnosis: persistent splenomegaly (> 10 cm below the costal margin), increased anti-Plasmodium antibodies, increased IgM levels, exclusion of other causes of splenomegaly or malignancy, and a favorable response to antimalarial treatment. We describe the case of a 16-year-old patient, who recently arrived... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2019 |
Schlagwörter: | Sciences bio-médicales et agricoles / Adolescent / Antibodies / Protozoan -- blood / Antimalarials -- therapeutic use / Artemisinins -- therapeutic use / Belgium / Chronic Disease / Drug Therapy / Combination / Guinea / Humans / Malaria / Falciparum -- complications -- immunology / Male / Nucleic Acid Amplification Techniques / Plasmodium falciparum -- genetics / Quinolines -- therapeutic use / Splenomegaly -- diagnosis -- immunology -- parasitology / Temperature |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27368508 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/357789 |