Genetic variability among complete human respiratory syncytial virus subgroup A genomes: bridging molecular evolutionary dynamics and epidemiology
Human respiratory syncytial virus (RSV) is an important cause of severe lower respiratory tract infections in infants and the elderly. In the vast majority of cases, however, RSV infections run mild and symptoms resemble those of a common cold. The immunological, clinical, and epidemiological profile of severe RSV infections suggests a disease caused by a virus with typical seasonal transmission behavior, lacking clear-cut virulence factors, but instead causing disease by modifying the host's immune response in a way that stimulates pathogenesis. Yet, the interplay between RSV-evoked immune re... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2012 |
Schlagwörter: | Amino Acid Substitution / Base Sequence / Bayes Theorem / Belgium / Child / Preschool / DNA Primers / Evolution / Molecular / Genetic Variation / Genome / Viral / Genomics / Humans / Infant / Newborn / Models / Genetic / Molecular Sequence Data / Mutation Rate / Netherlands / Real-Time Polymerase Chain Reaction / Respiratory Syncytial Virus Infections / Respiratory Syncytial Virus / Human / Selection / Sequence Analysis / DNA / Viral Envelope Proteins / Journal Article / Research Support / Non-U.S. Gov't |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27352877 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/272574 |