P496 Efficacy and safety of ustekinumab for chronic antibiotic refractory pouchitis: A Belgian open-label multicentre pilot study
Abstract Background Up to 10% of ulcerative colitis patients who undergo a proctocolectomy with ileal pouch-anal anastomosis, will develop chronic antibiotic refractory pouchitis (CARP). As there is a large unmet need in the management of these patients, we evaluated the efficacy and safety of induction therapy with ustekinumab (UST) for this indication. Methods We performed a prospective, Belgian, multicentre, open-label study of patients with CARP. Patients received a weight-range-based infusion of UST at baseline (6mg/kg) and one subcutaneous injection of 90mg UST at week 8. The first 4 wee... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2022 |
Reihe/Periodikum: | Journal of Crohn's and Colitis ; volume 16, issue Supplement_1, page i460-i461 ; ISSN 1873-9946 1876-4479 |
Verlag/Hrsg.: |
Oxford University Press (OUP)
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Schlagwörter: | Gastroenterology / General Medicine |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27316313 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1093/ecco-jcc/jjab232.623 |