Adult final height after GH therapy for irradiation-induced GH deficiency in childhood survivors of brain tumors: the Belgian experience.
peer reviewed ; OBJECTIVES: The treatment of brain tumors in childhood is frequently complicated by growth retardation with a high proportion of irradiation (Irr)-induced GH deficiency (GHD) resulting in reduced adult final height (AFH) even after GH therapy (GHT). In order to optimize future GHT protocols, more information on the factors influencing the growth response to GH in these children is needed. This retrospective study evaluated AFH and influencing auxological and treatment factors of a standardized daily biosynthetic GHT in childhood survivors of brain tumors with documented GHD aft... Mehr ...
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Dokumenttyp: | journal article |
Erscheinungsdatum: | 2010 |
Verlag/Hrsg.: |
BioScientifica Ltd
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Schlagwörter: | Adolescent / Adult / Age Factors / Belgium / Body Height/drug effects/radiation effects / Brain Neoplasms/radiotherapy / Chi-Square Distribution / Child / Preschool / Databases / Factual / Female / Human Growth Hormone/deficiency/therapeutic use / Humans / Hypopituitarism/etiology / Infant / Male / Patient Selection / Pituitary Gland/physiopathology/radiation effects / Radiotherapy/adverse effects / Regression Analysis / Retrospective Studies / Sex Factors / Statistics / Nonparametric / Survivors / Human health sciences / Endocrinology / metabolism & nutrition / Sciences de la santé humaine / Endocrinologie / métabolisme & nutrition |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27313341 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://orbi.uliege.be/handle/2268/109521 |