Phylogenetic analysis of the Belgian HIV-1 epidemic reveals that local transmission is almost exclusively driven by men having sex with men despite presence of large African migrant communities

To improve insight in the drivers of local HIV-1 transmission in Belgium, phylogenetic, demographic, epidemiological and laboratory data from patients newly diagnosed between 2013 and 2015 were combined and analyzed. Characteristics of clustered patients, paired patients and patients on isolated branches in the phylogenetic tree were compared. The results revealed an overall high level of clustering despite the short time frame of sampling, with 47.6% of all patients having at least one close genetic counterpart and 36.6% belonging to a cluster of 3 or more individuals. Compared to patients on... Mehr ...

Verfasser: Verhofstede, Chris
Stoffels, Karolien
Ribas, Sergio García
Dessilly, Géraldine
Debaisieux, Laurent
Pierard, Denis
Van Ranst, Marc
Hayette, Marie-Pierre
Deblonde, Jessika
Sasse, André
Van Beckhoven, Dominique
Dauwe, Kenny
Mortier, Virginie
Fransen, Katrien
Van Laethem, Kristel
Van den Wijngaert, Sigi
Ruelle, Jean-Louis
Delforge, Marc
Vancutsem, Ellen
Vaira, Dolores
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Schlagwörter: Pathologie maladies infectieuses / Ecologie / Evolution des espèces / Biologie / Biologie moléculaire / Microbiologie et protistologie [bacteriol.virolog.mycolog.] / Microbiologie et protistologie [entomologie / phytoparasitolog.] / Microbiologie et protistologie [parasitologie hum. et anim.] / HIV-1 in Belgium / HIV-1 in Sub-Saharan African migrants / HIV-1 transmission / Men who have sex with men / Phylogenetic clustering
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-27303346
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/269448