Prevalence of activated protein C resistance and analysis of clinical profile in thromboembolic patients. A Belgian prospective study
Objectives. To assess the prevalence of activated protein C resistance (APC‐R) among healthy subjects and thromboembolic patients and to determine the clinical characteristics associated with APC‐R. Design. A prospective study. Setting. One academic medical centre. Subjects. 91 health controls and 126 thromboembolic patients. Measurements. Patients and control were genotyped for the factor V Leiden (VaQ506) mutation. The anticoagulant response of the patient's plasma to activated protein C was also determined. Results. The frequency of APC‐R was 3.3% among healthy control subjects and 22% amon... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 1997 |
Reihe/Periodikum: | Journal of Internal Medicine ; volume 241, issue 5, page 427-433 ; ISSN 0954-6820 1365-2796 |
Verlag/Hrsg.: |
Wiley
|
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27300361 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1046/j.1365-2796.1997.139145000.x |