Adult final height after GH therapy for irradiation-induced GH deficiency in childhood survivors of brain tumors: the Belgian experience

Objectives The treatment of brain tumors in childhood is frequently complicated by growth retardation with a high proportion of irradiation (Irr)-induced GH deficiency (GHD) resulting in reduced adult final height (AFH) even after GH therapy (GHT). In order to optimize future GHT protocols, more information on the factors influencing the growth response to GH in these children is needed. This retrospective study evaluated AFH and influencing auxological and treatment factors of a standardized daily biosynthetic GHT in childhood survivors of brain tumors with documented GHD after brain Irr. Des... Mehr ...

Verfasser: Beckers, D
Thomas, M
Jamart, J
Francois, I
Maes, M
Lebrethon, M C
De Waele, K
Tenoutasse, S
De Schepper, J
Dokumenttyp: Artikel
Erscheinungsdatum: 2010
Reihe/Periodikum: European Journal of Endocrinology ; volume 162, issue 3, page 483-490 ; ISSN 0804-4643 1479-683X
Verlag/Hrsg.: Oxford University Press (OUP)
Schlagwörter: Endocrinology / General Medicine / Diabetes and Metabolism
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-27294808
Datenquelle: BASE; Originalkatalog
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Link(s) : http://dx.doi.org/10.1530/eje-09-0690