NEUTRALIZATION OF ARUBA RATTLESNAKE (CROTALUS UNICOLOR) VENOM ACTIVITY USING A POLYVALENT (ANTI-VIPERIDAE) VENEZUELAN ANTIVENIN

Crotalus unicolor is a endemic species of the Neotropical rattlesnakes, which it is only found on the Island ofAruba, located off the coast of Venezuela. In a comparative study using SDS-PAGE C. unicolor venom has similarbands as several Venezuelan rattlesnake venoms. At least 6 different bands of approximately 210, 116, 114, 110,96 and 52 kDa were shared among C. unicolor and other Venezuelan rattlesnakes tested. Precipitation lines in animmunodiffusion assay exhibited many antigen-antibodies determinants in venom proteins and antivenin.