Natural Human Infections With Plasmodium cynomolgi and Other Malaria Species in an Elimination Setting in Sabah, Malaysia
Abstract To determine the presence and species composition of malaria infections, we screened a subset of samples collected during a cross-sectional survey in Northern Sabah, Malaysia using highly sensitive molecular techniques. Results identified 54 asymptomatic submicroscopic malaria infections, including a large cluster of Plasmodium falciparum and 3 P. knowlesi infections. We additionally identified 2 monoinfections with the zoonotic malaria Plasmodium cynomolgi, both in individuals reporting no history of forest activities or contact with macaques. Results highlight the need for improved... Mehr ...
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| Dokumenttyp: | Artikel |
| Erscheinungsdatum: | 2019 |
| Reihe/Periodikum: | The Journal of Infectious Diseases ; volume 220, issue 12, page 1946-1949 ; ISSN 0022-1899 1537-6613 |
| Verlag/Hrsg.: |
Oxford University Press (OUP)
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| Schlagwörter: | Infectious Diseases / Immunology and Allergy |
| Sprache: | Englisch |
| Permalink: | https://search.fid-benelux.de/Record/base-27278500 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | http://dx.doi.org/10.1093/infdis/jiz397 |
Abstract To determine the presence and species composition of malaria infections, we screened a subset of samples collected during a cross-sectional survey in Northern Sabah, Malaysia using highly sensitive molecular techniques. Results identified 54 asymptomatic submicroscopic malaria infections, including a large cluster of Plasmodium falciparum and 3 P. knowlesi infections. We additionally identified 2 monoinfections with the zoonotic malaria Plasmodium cynomolgi, both in individuals reporting no history of forest activities or contact with macaques. Results highlight the need for improved surveillance strategies to detect these infections and determine public health impacts.