Formulations Slow Release Tablet Diclofenac Sodium Using Starch From Saba Banana (Musa Balbisiana L)
The formulation of slow release tablet of diclofenac sodium using a matrix of starch from saba banana and sodium carboxyl methyl cellulose as a comparison has been done. The purpose of this study was to determine whether the slow-release preparations produced with starch from saba banana met the requirements of slow-release tablet . The dissolution test results show the formula I (starch of saba banana) was dissolved 110.24 %, formula II ( sodium carboxyl methyl cellulose ) was disolved 39.04 % within 8 hours. The dissolution test results showed that starch of saba banana did not meet the requ... Mehr ...
| Verfasser: | |
|---|---|
| Dokumenttyp: | Journal:earticle |
| Erscheinungsdatum: | 2016 |
| Verlag/Hrsg.: |
Indonesian Pharmacist Association
|
| Schlagwörter: | Indonesia / pisang kepok / pati / lepas lambat / matriks / Farmasetika / kepok banana / starch / sustained release / matrix / Pharmaceutics |
| Sprache: | Indonesian |
| Permalink: | https://search.fid-benelux.de/Record/base-27255332 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://www.neliti.com/publications/128564/formulations-slow-release-tablet-diclofenac-sodium-using-starch-from-saba-banana |
The formulation of slow release tablet of diclofenac sodium using a matrix of starch from saba banana and sodium carboxyl methyl cellulose as a comparison has been done. The purpose of this study was to determine whether the slow-release preparations produced with starch from saba banana met the requirements of slow-release tablet . The dissolution test results show the formula I (starch of saba banana) was dissolved 110.24 %, formula II ( sodium carboxyl methyl cellulose ) was disolved 39.04 % within 8 hours. The dissolution test results showed that starch of saba banana did not meet the requirements as a matrix because it could not not reduce the rate of dissolution . The kinetics of the release of active substances from the matrix between the two formulas followed Higuchi equation .